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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOPEY2
All Species:
20.3
Human Site:
T648
Identified Species:
34.36
UniProt:
Q9Y3R5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3R5
NP_005119.2
2298
258184
T648
N
I
F
G
V
Q
L
T
A
S
G
E
E
S
K
Chimpanzee
Pan troglodytes
XP_531552
2298
258112
T648
N
I
F
G
V
Q
L
T
A
S
G
E
E
S
K
Rhesus Macaque
Macaca mulatta
XP_001084653
2286
256620
T636
N
I
F
G
V
Q
L
T
A
S
G
E
E
S
K
Dog
Lupus familis
XP_544874
2297
257913
T648
N
I
F
G
V
Q
V
T
T
S
G
E
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHQ6
2295
257491
T648
N
I
F
A
A
S
L
T
V
S
G
E
E
N
K
Rat
Rattus norvegicus
XP_001055500
2294
257490
T647
N
I
F
A
A
S
L
T
V
S
G
E
E
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512569
2247
251024
P648
N
L
L
G
A
P
G
P
G
D
E
T
P
S
A
Chicken
Gallus gallus
XP_001232723
2283
257889
Q646
Y
I
F
G
V
Q
F
Q
E
A
N
N
E
S
I
Frog
Xenopus laevis
Q642P2
2270
256829
I644
A
S
K
H
L
F
R
I
Q
L
K
G
E
G
Q
Zebra Danio
Brachydanio rerio
NP_956904
817
86774
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
A1ZBE8
2599
291169
N671
D
M
V
L
I
Q
S
N
T
S
A
E
V
S
D
Honey Bee
Apis mellifera
XP_395999
2434
273219
I635
R
N
K
S
M
D
D
I
K
T
G
Y
I
E
T
Nematode Worm
Caenorhab. elegans
Q9XW10
2417
267134
L725
V
S
A
R
A
S
L
L
E
L
L
C
K
I
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03921
1698
194669
S135
Y
A
S
M
S
V
R
S
H
L
I
E
L
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
94.8
89.9
N.A.
86.4
86.4
N.A.
73.9
75.2
69
21.9
N.A.
27.6
32.1
22.3
N.A.
Protein Similarity:
100
99.7
96
94.6
N.A.
92.4
92.5
N.A.
83
85.4
82
28.7
N.A.
47
53.2
40.9
N.A.
P-Site Identity:
100
100
100
80
N.A.
66.6
73.3
N.A.
20
46.6
6.6
0
N.A.
26.6
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
26.6
53.3
20
0
N.A.
46.6
20
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
15
29
0
0
0
22
8
8
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
8
0
0
0
0
8
8
0
0
8
0
0
0
8
15
% D
% Glu:
0
0
0
0
0
0
0
0
15
0
8
58
58
8
0
% E
% Phe:
0
0
50
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
43
0
0
8
0
8
0
50
8
0
8
0
% G
% His:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
8
0
0
15
0
0
8
0
8
8
8
% I
% Lys:
0
0
15
0
0
0
0
0
8
0
8
0
8
0
43
% K
% Leu:
0
8
8
8
8
0
43
8
0
22
8
0
8
0
0
% L
% Met:
0
8
0
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
8
0
0
0
0
0
8
0
0
8
8
0
8
0
% N
% Pro:
0
0
0
0
0
8
0
8
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
43
0
8
8
0
0
0
0
0
8
% Q
% Arg:
8
0
0
8
0
0
15
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
8
8
8
22
8
8
0
50
0
0
0
50
0
% S
% Thr:
0
0
0
0
0
0
0
43
15
8
0
8
0
0
8
% T
% Val:
8
0
8
0
36
8
8
0
15
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _